Social Impact

Come end of term, the Henry and Marilyn Taub Faculty of Computer Science at the Technion held its annual projects fair, showcasing projects by undergraduate students in their final year. Given freedom to choose how they will apply the principles learned in the course of their studies, multiple groups chose to help the community, and more than one partnered with the Technion Social Hub to do so.

The students’ projects and the partnership with the Technion Social Hub present a unique opportunity: small NGOs often find themselves in need of a software solution but can neither find an existing platform to cover their particular needs, nor afford custom software. This is just the demand students can meet, at the same time gaining valuable experience in serving a client.

This year, three such projects stood out among the rest.

Friends for Health team
Friends for Health Team

First, a project for Friends for Health, by Ido Yam, Tal Manheim, Yaakov Sherma, Illay Hai, and Daniel Shapiro, guided by Eytan Singher and Itai Dabran. Friends for Health is a nonprofit organization dedicated to helping people who cannot afford the life-saving medication they need. Their stock comes from donors who have unused medications that they are willing to donate. The Technion team wrote for the organization a computerized interface – for the patients, it guides them to the appropriate form for receiving the specific medication they need; for donors – organizing the donation, adding the possibility for medications to be collected from the donor’s home (necessary for medications with strict storage requirements); for employees – management functions. These functions, which we take for granted in a commercial company, were previously done manually in this important nonprofit. The students’ software would considerably shorten waiting times and enable Friends for Health to assist more patients.

Social Delivery team
Social Delivery Team

A similar project was provided for Social Delivery by Lior Zelikman, Alex Chirkov, Yagel Meir and Tal Neoran, guided by Eytan Singher and Itai Dabran. Social delivery is an initiative offering logistical solutions for connecting between excess stocks of various objects (furniture, textiles, etc.) and NGOs needing those objects. Recently, they are also looking into adding companies replacing office furniture as potential donors. The students digitized for the first time the initiative’s donations, requests and storage tracking. The new interface even lets donors see their past donations and which NGOs they had helped.

A project of a different sort is the Hadar Social Network, by Haneen Jeries, Hussein Abu Jabal, Sami Hammoud and Haitham Kablan, guided by Elazar Gershoni and Itai Dabran. Hadar is considered a disadvantaged neighborhood in the City of Haifa, and the Technion is located nearby. Over the past years, the neighborhood has come to organize, and people started assisting each other however they can. But everything was happening over disjointed WhatsApp conversations, making it difficult to keep track of what was going on, or administrate the interactions. The students partnered with the neighborhood council to create a dedicated app, providing a smooth and secure process of connecting volunteers with people who need help. An administrator can ensure the security of the interaction, and a community social worker can use it to provide assistance.

Hadar Social Network team
Hadar Social Network Team

These projects were by no means the only ones that sought to combine a homework assignment with a chance to do good. Other groups dealt with fair trade, donation of excess food from restaurants, accessibility mapping and more. For Technion students, academic success and helping those less privileged go hand in hand.

Growing Lymph Vessels in a Lab

Technion scientists have managed to grow an engineered human lymphatic vessel network. Published in PNAS, the study was led by postdoctoral fellow Dr. Shira Landau and conducted in the laboratory of Professor Shulamit Levenberg of the Technion Faculty of Biomedical Engineering. The significance of the researchers’ findings lies in a better understanding of lymphatic vessel generation, which could have implications for treatment of lymphedema and the generation of more lifelike tissue flaps.

Prof. Shulamit Levenberg and Dr. Shira Landau

The lymphatic vessels are built similar to veins. They collect the fluid between the cells in all body tissues. This lymphatic fluid is collected by lymph capillaries, then transported via progressively larger lymphatic vessels through lymph nodes, before emptying ultimately into major veins. The lymphatic system also plays an important role in the body’s immune response. Damage to the lymphatic vessels results in localized swelling, a condition called lymphedema. Lymphedema currently has no cure. Common treatments that provide partial improvement include compression of the affected limb and massage. In severe cases, bypass surgery is prescribed.

In the lab, Dr. Shira Landau and her coresearchers grew human lymphatic vessels, together with blood vessels and supporting cells, creating engineered tissue with a functioning vessel network. This was done from inner-lining cells of lymphatic vessels, together with blood vessels respectively, together with support cells, all seeded on sheets of collagen – the main structural protein of the body’s connective tissue. That is, their engineered tissue mimics as closely as possible the body’s natural structures. From this seemingly simple starting point, the group had within a few days a network of vessels that displayed both the arrangement and the functionality expected of them in the body. The engineered tissue was further implanted into a mouse, and successfully integrated with the mouse’s lymph and blood vessels.

This success by the Technion scientists has multiple implications. First, the platform they grew would facilitate the study of lymphatic vessels, their formation, and the factors that affect them. Second, lymphedema, which currently lacks effective treatment, could be in the future treated by implanting a functional network of smaller and larger lymph vessels that would merge with the host’s system, all grown from the patient’s own cells, eliminating fear of rejection. Third, engineered tissue flaps, that is units containing multiple tissues necessary for transplantation, such as muscle, blood vessels, and connective tissue, could be made more lifelike, containing lymph vessels as well. This would improve the implant’s integration and speed up healing.

בתמונת המיקרוסקופ: מבנה מהונדס שהושתל בעכבר. בירוק: הרשת הלימפטית המושתלת; בכחול: הרשת הלימפטית של העכבר מתחברת לרשת המושתלת.
An engineered structure implanted in a mouse. Green: the transplanted lymphatic network; In blue: the mouse lymphatic network connects to the transplanted network

Click here for the paper in PNAS

Groundbreaking Imagery

Researchers at the Technion – Israel Institute of Technology have developed an innovative rapid imaging technology and demonstrated its performance in reconstructing the movement of a minute animal. Published in Nature Communications, the development project was headed by Professor Amir Rosenthal, doctoral student Evgeny Hahamovich, and master’s student Sagi Monin of the Andrew and Erna Viterbi Faculty of Electrical and Computer Engineering.

         

Images: Visualizing the movement of C. elegans with the new technology. Creating such videos had not been previously feasible with SPI technologies.

The research team’s technology is based on the innovative SPI (single-pixel imaging) concept – the production of high-quality images using a device equipped with only a single detector. This concept, which enables photographs to be taken without a camera, has vast potential for diverse applications, such as the development of components of warning systems in autonomous vehicles or enhanced image depth in microscopy of biological tissues.

SPI is based on the illumination of an object with encoded light patterns, generally by means of a projector. Based on the properties of the light reflected and propagated by the object, the image of the object can be produced using reconstruction algorithms. The problem is that to date, these systems have been hampered by significant limitations, one of them being the slow image acquisition rate, which is the result of the fact that the projectors themselves are slow. This has, until now, limited use of the systems to photographing stationary objects.

The Technion research team broke through this limitation by applying a new method for spatially encoding light at unprecedented frequencies – 2.4 MHz as opposed to 22 kHz, which is the maximum frequency currently available in SPI technology. This represents an improvement of more than a hundredfold in projection rates and image acquisition rates. By using a rotating device fitted with a coding mask, the researchers created a completely new illumination pattern and an SPI microscope with unprecedented capabilities.

To demonstrate the system’s capabilities, the research group produced videos with a frame rate of 72 FPS (frames per second). The films accurately depict the complex movement of the nematode worm, C. elegans, an impossible achievement using currently available SPI technology.

The study was funded by the Ollendorf Minerva Center.

Click here for the paper in Nature Communications

פרופ' אמיר רוזנטל
Professor Amir Rosenthal
הדוקטורנט יבגני חכמוביץ'
Doctoral student Evgeny Hahamovich
המסטרנט שגיא מונין
Master’s student Sagi Monin

A Matter of Perspective

Technion students taking a one-of-a-kind course called “A Matter of Perspective” – a collaboration of the Henry and Marilyn Taub Faculty of Computer Science and the Faculty of Architecture and Town Planning – recently showcased their final projects. The class engaged students in using digital manufacturing technologies to produce a physical product, through the realization of a geometric algorithm.

The class gave an opportunity to both architecture and computer science students to work together in small teams, exposed to each other’s worlds. They then submitted a final project, which included an algorithm that produces geometry, and a physical object produced using digital technologies (e.g. 3D printing or laser cutting).

Among the final projects were:

  • A printed object that casts a shadow in various shapes when rotated
  • 3D “eclairs” dominated by a pattern of laser-cut parameters based on oxidation shape
  • A printed object that contains three different images, which reveal themselves depending on the direction from which you look at them
  • 3D-printed lenses with transparency and color transitions that create shapes projected on the wall

The course was taught by Prof. Gershon Elber (Computer Science), Prof. Miri Ben-Chen (Computer Science), Yoav Sterman (Architecture) and Kacper Pluta (Computer Science, TA).

“By combining the creativity and design capabilities of architecture students with the computational mindset and algorithmic abilities of computer science students, this course has the potential to create holistic ideas and designs that go much further than what each discipline can create individually,” the professors say. “Specifically, computational tools allow for easy automation and form finding, whereas the design aspect drives shape exploration towards functional and inspiring objects.”

They added that, in the long term, the course can be a stepping stone towards joint research and collaboration between the two faculties. The course A Matter of Perspective will be taught again in the Spring semester of 2022.

3D “eclairs”

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Water From Air

H2OLL, an innovative Atmospheric Water Generator (AWG) technology developed at the Technion – Israel Institute of Technology, has won the prestigious Water Europe Innovation Award for SMEs. The award was announced in June at the Water Innovation Europe 2021 Conference. Water Europe (WE) is a European technology platform for collaboration between research institutes, companies, and water utilities. The Water Europe platform was initiated by the European Commission in 2004, and now encompasses more than 200 commercial businesses, academic and research bodies, and water supply companies whose collective goal is to build a water-smart economy in Europe.

More than 10% of the world’s population, over 670 million people, presently have no access to clean drinking water, which significantly impacts numerous aspects of their lives, including health, education, and gender equality. H2OLL’s Atmospheric Moisture Harvesting (AMH) technology is capable of extracting moisture from the air even in arid and desert regions, and is highly relevant to many of the UN’s Sustainable Development Goals, including the rights of every person for clean water, good health, and well-being, climate action, quality education, and gender equality (in many places in the world, children – girls in particular – are required to provide water to the family at the expense of attending classes at school).

The H2OLL technology was developed by Professors David Broday and Eran Friedler from the Faculty of Civil and Environmental Engineering and was patented by the Technion. The development team is headed by Mr. Ilan Katz (M.Sc.) as CTO, Mr. Oded Distel who leads the business development, and Dr. Khaled Gommed from the Faculty of Mechanical Engineering.

The Technion research team built a prototype at the Technion’s Environmental Technologies Yard, which has been producing potable water since the winter of 2019-2020 (i.e. throughout the COVID-19 pandemic) and serves as a proof of concept (POC). Award-winning company H2OLL is en route to becoming a company and to commercializing the technology, with Mr. Ilan Katz as its CEO and Mr. Oded Distel as VP for business development.

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Trailblazing AI Research

Technion researchers are harnessing the power of artificial intelligence (AI) to tackle the world’s most-pressing challenges. Their extensive work in the field has positioned the Technion among the world’s leaders in AI research and development. CSRankings, the leading metrics-based ranking of top computer science institutions around the world, has ranked the Technion No. 1 in the field of artificial intelligence in Europe, and 15th worldwide. In the subfield of machine learning, the Technion is ranked 11th worldwide.

Over the years, the Technion has carried out outstanding research in the field of AI – much of which has developed into trailblazing commercial products. Collaborations with manufacturers, the high-tech industry, government agencies, R&D centers, healthcare providers and academic institutions, have all contributed to the Technion’s excellence in the field, and many alumni and researchers have gone on to found companies across the AI spectrum.

Technion’s Summer 2021 AI Brochure

During the coronavirus pandemic, Technion researchers and alumni have used a host of AI technologies, from detection to diagnostics, including testing for pre-symptomatic COVID-19 carriers; predicting the spread of COVID-19 around the globe; and analyzing the data of thousands of patients to show the effectiveness of the COVID-19 vaccine.

To learn about the Technion’s groundbreaking AI research and technologies, click to read our Summer 2021 AI Brochure.

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Fast-Charging Batteries

Professor Yair Ein-Eli
Professor Yair Ein-Eli

Fast charging is considered to be a key requirement for widespread economic success of electric vehicles. Current lithium-ion batteries (LIBs) offer high energy density, but while they enable sufficient driving range, they take considerably longer to recharge than traditional vehicles. Multiple properties of the applied anode, cathode, and electrolyte materials influence the fast-charging ability of a battery cell.

In a review published this month in the high impact Journal Advanced Energy Materials, an international team of researchers considers in detail the physicochemical basics of different material combinations, and identify the transport of lithium inside the electrodes as the crucial rate-limiting steps for fast-charging. The group* headed by Professor Yair Ein-Eli and graduate student Ms. Natasha Ronit Levy from the Technion Department of Materials Science and Engineering, and Professor Jürgen Janek and Dr. Manuel Weiss from Giessen University (Institute of Chemical Physics, Germany), identified that lithium-ion diffusion and migration within the active materials inherently slows down the charging process and impose high resistivity.

In addition, concentration polarization by a slow lithium-ion transport within the electrolyte phase in the porous electrodes also limits the charging rate. Both kinetic effects are responsible for lithium plating observed on the graphite anodes. Such plating of metallic lithium may lead to a dangerous thermal runaway, resulting in explosion and fire. The conclusions drawn by the researchers from potential and concentration profiles within LIB cells are complemented by extensive literature surveys on anode, cathode, and electrolyte materials. They analyzed advantages and disadvantages of typical LIB materials and offered suggestions for optimum properties on the material and electrode level for fast-charging applications.

Ronit Natasha Levy
Ronit Natasha Levy

* The research groups that took part in the review work were part of the 4th German-Israel Batteries School held in Berlin in 2019: from Israel – Prof. Yair Ein-Eli [Technion] and Prof. Doron Aurbach [Bar-Ilan University]; From Germany – Prof. Jürgen Janek [Giessen University], Prof. Martin Winter [Münster University], and Prof. Margaret Wohlfahrt-Mehrens [Energy Research Center, Ulm]. Financial support was provided by the following entities and foundations: the German Federal Ministry for Education and Research (BMBF) within GIBS 4 bi-national workshop, the Federal Ministry for Economic Affairs and Energy (BMWi), the Israeli Ministry of Science and Technology (MOST), the Planning & Budgeting Committee/Israel Council for Higher Education (CHE), and Fuel Choice Initiative (Prime Minister Office) within the framework of “Israel National Research Center for Electrochemical Propulsion” (INREP 2) and by the Grand Technion Energy Program (GTEP).

Click here for the paper in Advanced Energy Materials

Towards a Greener Technion

In less than three months, on October 1, 2021, the Technion – Israel Institute of Technology will stop buying disposable utensils. The decision by Technion Executive Vice President & Director General Professor Boaz Golany came after a lengthy research study and a thorough review of the alternatives.

In 2019, the Technion bought more than 2.3 million disposable cups, almost one million disposable teaspoons, and hundreds of thousands of other single-use items. Disposable utensils currently account for approximately 9% of waste on campus, and the present move is intended to reduce the amount of waste and reduce associated expenses.

In 2019, the Technion bought more than 2.3 million disposable cups

In parallel to the CEO’s decision, the Technion will be providing its faculties and units with information on relevant and more environmentally friendly alternatives. Until adequate alternatives are found, the decision excludes cafeterias and small events held in the faculties. It is important to note, however, that even in these cases, the Technion will encourage a shift to reusable plates, cups, and cutlery.

“This is a comprehensive move that encompasses the Technion as a whole, and its implications are far-reaching,” said Prof. Golany. “In the past few years, the Technion has shifted into high gear in all aspects touching upon sustainability. Two important milestones that preceded the present move are the approval of Technion’s Strategic Plan of 2016 and the Technion Comptroller’s Report of 2019, which led to important recommendations related to sustainability. Our handling of these issues integrates research, teachings, and practices, which means that we will be placing special emphasis on promoting additional science-based steps that have the potential to bring about dramatic positive change.”

The move is being led by the Technion’s Sustainability Hub under the academic guidance of Professor Daniel Orenstein, who has authored important research on the issue of sustainability at universities, and the Hub’s coordinator, Dr. Ronit Cohen Seffer.

“Our view of sustainability and material consumption is holistic, and encompasses all potential responses: reduce, reuse and recycle,” said Prof. Orenstein. “There is no doubt that recycling is important, but reuse and reduction are especially important goals because they prevent pollution already in the production phase.” The production phase of disposable utensils is accompanied by emissions of toxic substances and greenhouse gases, and the transportation of the goods is also the source of a great deal of pollution.

“Before making this decision, we studied every aspect of the alternative – the use of reusable utensils – and we recognize that in addition to discontinuing the use of disposables, we must provide instructions on the right way to reduce the environmental impact of the alternative, too,” added Prof. Orenstein. “It is important to place consumption habits in a much broader context, which is the attempt to minimize damage to the environment on all fronts: energy, waste, land pollution, water and air pollution, and others.”

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Language Matters

There is a saying that all the world’s knowledge is available at our fingertips – just a quick Google search away. But what happens when users search for information in their own language? For example, when searching for a scientific term, do search engines provide English-, Hebrew- and Arabic-speaking students with the same level of access to quality scientific information? This question is addressed by a new study, conducted at the Technion – Israel Institute of Technology and recently published in Public Understanding of Science.

Clockwise from top left: Professor Ayelet Baram-Tsabari, Kayther Zoubi, Dr. Aviv Sharon, Dr. Eyal Nitzany

The study found that search results for terms in English are of better quality than those provided for equivalent terms in Hebrew and Arabic. Additionally, most of the differences between the languages pertained to pedagogical aspects of quality, that is, the extent to which the content was geared towards young users, rather than the scientific aspects, such as the accuracy of the content. Some of the largest differences between the languages were found for terms related to nutrition and metabolism, such as “carbohydrate,” “protein,” “enzyme,” and “metabolism.”

These findings are based on the top Google Search results presented to users in Israel for 30 basic scientific terms in three languages: Hebrew, Arabic, and English. The terms pertained to three scientific domains: biology, chemistry, and physics. Each search result’s overall quality was determined using scientific criteria, such as content accuracy, the author’s authority, and the use of sources; pedagogical criteria, such as references to everyday life and the quality of audiovisual materials; and criteria specific to online content, such as recency and interactivity.

According to Kawther Zoubi, who conducted the study as part of her masters’ thesis in the Technion’s Faculty of Education in Science and Technology, “these findings help us understand the digital divide and the social factors that affect our ability to develop science literacy. Our understanding of science depends on the environment we live in and the extent to which we have access to quality scientific information. This depends on our proficiency in different languages.”

Professor Ayelet Baram-Tsabari of the Faculty of Education in Science and Technology, who oversaw the study, added that, “The scientific and educational communities must act to mitigate the digital divide. We all have the right to access quality scientific information in our language.”

Click here for the paper in Public Understanding of Science.

Video demonstrating the study:

Cells Expressing Tendon Markers Fuse into Muscles

Researchers at the Rappaport Faculty of Medicine at the Technion – Israel Institute of Technology have made a breakthrough discovery that muscle fibers are of hybrid origins, and their tips have a “fibroblastic, tendon-like property” that arises from fibroblasts’ fusion. The researchers’ findings highlight a mechanism that enables a smooth transition from muscle fiber characteristics towards tendon features that is essential for forming robust muscle tendon junctions (MTJs). The research was recently published in Nature Communications.

Professor Peleg Hasson (right) and doctoral student Wesal Yaseen Badarneh
Professor Peleg Hasson (right) and doctoral student Wesal Yaseen Badarneh

Using innovative techniques for analyzing single cells (scRNAseq), Professor Peleg Hasson and doctoral student Wesal Yaseen Badarneh reexamined the classical view of distinct identities for the tissues composing the musculoskeletal system. They identified a novel cluster of cells, which they termed dual identity cells. These dual identity cells are fibroblast-derived, yet express myogenic transcriptional programs and fuse into the tips of the developing muscle fibers along the muscle tendon junctions, facilitating the introduction of fibroblast-specific transcripts into the elongating myofibers.

Tendons are the connective tissues that connect between the muscles and bones. Consequently, the tendons’ mechanical properties are crucial in order for humans and other vertebrates to bear varying pressures and perform essential movements. When the development of MTJs is damaged, it may result in clinical phenomena including multiple types of muscle diseases. Therefore, understanding the molecular mechanism underlying MTJ development is very important.

Although vertebrate muscles and tendons are derived from distinct embryonic origins, they must interact in order to enable muscle contraction and body movements. It is still not understood how these two distinct tissues, each with its own biophysical and biochemical properties, form robust junctions that are able to withstand contraction forces. Prof. Hasson and his team identified fibroblasts that have switched on a myogenic program facilitating a seamless transition from a muscle fiber characteristic into a tendon-like structure. Their findings suggest that dual characteristics of junctional cells could be a common mechanism for generating stable interactions between tissues throughout the musculoskeletal system.

The research was carried out in collaboration with researchers from the University of Cincinnati College of Medicine and the Cincinnati Children’s Hospital Medical Center. It was supported by the Israel Science Foundation, the Rappaport Family Institute at Technion, Pew Charitable Trusts, and the National Institutes of Health (NIH).

Click here for the paper in Nature Communications

the RNA of LOXL3 in red, that of MYOD in purple and immunostaining of the muscle fibers in green.
Picture: the RNA of LOXL3 in red, that of MYOD in purple and immunostaining of the muscle fibers in green. The RNA of LOXL3 is expressed in the tendon and at the junction of the muscle while that of MYOD is expressed within the muscle. Hence what you see is the junction area, which at least according to the RNA expression model looks very sharp but in fact, there are hybrid cells there.

GTIIT Commencement

The first cohort graduated from the Guangdong Technion Israel Institute of Technology in a moving ceremony held earlier this week in China, where 149 students received their bachelor’s degrees.

הבוגרים בטקס
GTIIT graduates

“GTIIT is the first and only endeavor of its kind in the mutual history of China and Israel,” Technion President Prof. Uri Sivan, who joined the ceremony via videoconferencing, said at the event. “Two ancient nations, which share the values of knowledge, scholarship, and innovation for thousands of years, have bridged across geography and language to create the marvel that we celebrate today. He went on to say that the language of science “bridges geographies and cultures to connect all people for the benefit of humanity. It is this language, that you, dear graduates, have acquired at GTIIT.”

נשיא הטכניון פרופ' אורי סיון מברך את הבוגרים בטקס מחיפה
Technion President Prof. Uri Sivan speaks at the first GTIIT commencement 

Prof. Sivan congratulated the graduates, faculty, and leaders of GTIIT. He thanked Mr. Li Ka-shing, former GTIIT Chancellor Li Jiange, former Technion President Prof. Peretz Lavie, and the Technion Special Envoy to GTIIT, Nobel Laurette Distinguished Prof. Aaron Ciechanover. “The creation and success of GTIIT is the outcome of the work of many, both in Israel and in China,” Prof. Sivan said. “Still, we would not be here today without the profound vision, brilliant leadership, and deep devotion of these individuals to the idea, which is now a living fact.”

Prof. Gong Xingao, Chancellor of GTIIT, greeted the guests, graduates and faculty, and so did Technion faculty members Prof. Dganit Danino, and Prof. David Gershoni. Peleg Lewi, Consul General of Israel in Guangzhou, also spoke at the ceremony.

The Guangdong Technion-Israel Institute of Technology (GTIIT) was inaugurated in China. The project is the result of a historic partnership between the Li Ka Shing Foundation, the Guangdong Provincial Government, the Shantou Municipal Government and the Technion-Israel Institute of Technology.

To read the full story on the GTIIT website, click here

To watch the entire graduation ceremony: 

[su_youtube url=”https://youtu.be/vGxuF3K5-_w” width=”700″ height=”200″]

Photos and video courtesy of the GTIIT Office of News & Public Affairs

‘Technion LIVE’ July 2021

In a nano-optics breakthrough, Technion researchers observed sound-light pulses in 2D materials, using an ultrafast transmission electron microscope. The study, recording for the first time the propagation of combined sound and light waves in atomically thin materials, was published in the prestigious journal Science.

To read the full story and others – from Israel’s first visually impaired doctor to cutting-edge artificial intelligence research, click here.