HACKERS ahead… Technion defends cyber space.

Technion Students Hack OSPF, the Most Popular Routing Protocol on the Internet.

The attack was part of a student project in the Computer Science Department and has attracted substantial interest in two scientific conferences; the students will be awarded the Technion Amdocs Prize.

Alex Kirshon and Dima Gonikman, students in the Technion Computer Science Department, showed how to hack the OSPF routing protocol, the most common protocol on the internet. The attack was part of a student project in the Laboratory of Computer Communication and Networking. It attracted substantial interest in the two scientific conferences it was presented where it was presented. Alex and Dima, supervised by Dr. Gabi Nakibly and Itai Dabran, will be awarded the Technion Amdocs Prize for Best Project in Computer Science.

Hundreds of thousands of routers work on the internet, linking the different networks. Each router is supposed to “know” all the other routers and to “talk” to them (to obtain information about their neighbors and about networks connected to them). The incessant involvement of the routers in the transmission of this information encumbers them and diminishes their effectiveness. Hence, the internet is in fact split into autonomic systems that “talk” to each other. The routers in each such system “know” each another.

The most popular protocol for the transmission of information between routers in autonomic systems is OSPF. If it malfunctions, many messages will not reach their destination. Moreover, there is concern that these messages will reach the attacker of the protocol. Accordingly, stringent security measures are in place for the protocols of network routers.

One of the important defenses is called “fight-back”. When it is implemented – when a router recognizes that another router has sent data in its name – it immediately issues a correction.

With help from their supervisors, Alex Kirshon and Dima Gonikman “targeted” this correction. They triggered a fight-back from a router on the network, but immediately before it was sent, they sent a fight-back with false data that was received by some of the other routers. When these routers received the fight-back of the compromised router, they rejected it.

The “attacking” students also identified in advance which fight-back the attacked router will send, so that the other routers received it “without doubts or questions”.  From the moment they received the “fake” fight-back,  routers on the network have incorrect routing tables.

Such an attack can disrupt the entire operation of the autonomic system, prevent messages from reaching their destination and unnecessarily create substantial traffic on the network.

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1912-2012: Technion Timeline of a Century.

Landmark behind Time





The Technion’s historic building was designed by the renowned Jewish German architect, Alexander Baerwald. His design includes both oriental and European motives. It is built from sandstone quarried in Tantura and Atlit. The building was part of Baerwald’s plan of an open corridor leading directly to the bay. He also designed buildings that would line the road, of which some were built, indeed (e.g. the Hebrew Reali School). 

The building’s cornerstone was laid in 1912. The building’s construction was delayed during the First World War. The partially completed building was used, then, as a military hospital. In 1925 it became the home of Israel’s first institute of higher education – The Technion, Israel Institute of Technology. Until 1953, all the Technion Faculties were located there. By 1965, most of them have moved to the Technion new campus in Haifa’s Nave Shaanan. The Faculty of Architecture and Town Planning stayed in the historic Technion building until 1985. 


Timeline of the Century

2012: Technion partners with Cornell University to found the Technion Cornell Institute of Innovation (TCII), an international ‘School of Genius’ in the heart of New York City.


2011: Technion Prof. Dan Shechtman receives the Nobel Prize in Chemistry for his discovery of quasicrystals.


2007: Technion pools its brainpower in a unique multidisciplinary center for research into energy science, technology and engineering: The Grand Technion Energy Program.


2006: Technion is Israel’s 1st university to receive the Nobel Prize for Science. Prof. Aaron Ciechanover and Prof. Avram Hershko jointly receive the Nobel Prize in Chemistry for their discovery, together with Irwin Rose, of the ubiquitin system within living cells.


2005: Technion opens the Russell Berrie Nanotechnology Institute (RBNI) to further empower and concentrate the plethora of excellent scientists, researchers and students pioneering science in the nano dimension.


2001: Technion scientists reveal they have long been quietly researching solutions to meet the threat of 3rd millennium terrorism as revealed by the horrific events in the US of September 11th


1998: Combining microbiology and microelectronics, scientists show how to make a transistor 1/100,000th the size of a human hair


1993: Technion students design and launch their own satellite: Gurwin Tech Sat. The satellite is still in orbit.


1991: Gulf War – Technion shows that the integration of expertise of Israel’s top institute of technology with its dynamic medical school makes Technion first responders in responding to missile attack on the home-front.


1989: Optoelectronics: A new center of excellence pioneering the technological promise of an expert understanding of light.


1982: The Rappaport Family Institute for Research in the Medical Sciences is established. During more than two decades of activity, the Institute has established itself as an internationally recognized research center and counts among its members several world-renowned scientists.
1981: Fiberoptics is pioneered by Technion


1978: Camp David accords with Egypt: the scientific challenges of peace and nation-planning means that in addition to its many projects in water management and environmental engineering, the Technion sets up the Samuel Neaman Institute.


1973: Yom Kippur War


1971: The Faculty of Biology is set up.


1969: The faculty of medicine is born. The first class consists of 43 students who had their preclinical education abroad. They were admitted to the fourth year and finished the requirements for the degree of Medical Doctor (M.D.), after two years of clinical training in the hospitals. The same year also sees the birth of the Department of Biomedical Engineering and the Faculty of Computer Science. 


1967: Six-Day War, Faculty of Materials Engineering is set up.


1966: Agricultural engineering degrees awarded to students from Africa and Asia


1965: Department of Education in Technology and Science


1962: Faculty of Food Engineering and Biotechnology 


1961: Technion offers a  flourishing graduate school and R&D foundation


1960: The Faculty of Mathematics and the Faculty of Physics are formed.

1958:  The opening of the Faculty of Chemistry, the Faculty of Industrial Engineering and Management, and The  Department of Humanities and Arts

1956: Students take part in the Sinai War


1954: Technion founding father Prof. Albert Einstein is awarded a Technion honorary doctorate. The Faculty of Chemical Engineering is opened.


1953:The Department of Aeronautical Engineering and the  Faculty of Agricultural Engineering are set up in the new campus.


1952: Rapid growth and expansion and increasing demand for Technion graduates and engineers nation-wide means the Technion leaves its first home in the historic building in down-town Haifa. Prime-Minister David Ben Gurion selects the new site for Technion City further up the slopes of Mount Carmel.


1948: With 680 students, Technion celebrates the declaration of independence. Studies are disrupted for most of the year as faculty and students fight for independence. The Faculty of Electrical Engineering and the Faculty of Mechanical Engineering are opened.


1944: Survival tasks – Technion develops early warning systems against air attacks as well as weapons for the Hagannah, the Israeli underground army that are preparing for the War of Independence.


1943: 1000 skilled Technion graduates join the war effort against Nazi Germany


1938: The Faculties of civil engineering, architecture, industrial engineering and opened, together with 11 new labs and a nautical school


1935: The Polish government recognizes Technion
1934: The Faculty of Industrial Technology is established covering broad fields. 


1931: Technion staff vote to work for nothing to ensure their institute survives.
1928: First class of 17 Technion engineers and architects graduates


1926: Zeev Jabotinsky addresses Technion Haganah members


1924: Technion officially enrolls 1st class of engineering students


1923: Einstein’s first visit in which he becomes president of the first Technion society, the German Technion Society




 

In 1923, Albert Einstein visited the empty building of the Technikum, where there was a plan to give courses for word workers, electricians and telephone and telegraph workers. Although the derelict buildings were being used as a hostel for immigrants from Europe, Albert Einstein did not think the dream of founding a technical university in the Middle East to be fantasy. As a great scientist, Einstein knew that what makes the impossible possible is the courage to follow an inspiration. 


1920: The building is legally acquired and recruitment for staff begins


1914: 1918 German, Turkish and then British troops occupy the building


1913: A battle continues over the language of Technion instruction: German or revitalized Hebrew?   Hebrew wins.


1912: The cornerstone is laid for Technion’s building


1908: Wissotzky, Schiff and the Jewish National Fund invest in the new “Technikum” 


1903: Hebrew teachers association of Palestine calls for a polytechnic university


1902 Herzl publishes the novel Altneuland  (The Old New Land), which takes place in Palestine, creating the vision for a Jewish state and Zionism.


1901: 5th Zionist congress calls for a Jewish technological university, as a first necessary step to realize the dream of a Jewish state.


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We began with a thought…
           
“Our technical inventors, who are the true benefactors of humanity… will discover things as marvelous as those we have already seen, or indeed more wonderful than these…”
Theordor Herzl, 1896, The Jewish State

In 1902, Theodor Herzl envisioned Haifa as “a great park….with an overhead electrical train…. a city of magnificent homes and public institutions all made possible by applied science, engineering and technology.” (Altneuland)
At that time, even an automobile was an exceptional extravagance of engineering. Electricity was still an expensive luxury for the elite few.
Haifa was a small, remote, coastal town most easily accessed by boat.
The advance of science and technology; the creation of the State of Israel; the emergence of the global village connected by the information superhighway; discoveries in basic science that have fundamentally changed the way scientists think about the material world, and the tremendous applied advances taking place in every corner of Technion City are just some of the miracles witnessed in the past century.

It all began with an inspirational thought in the mind of one man, Binyamin Ze’ev Herzl. Prof. Albert Einstein later added his mind to the vision. Thousands of great thinkers have since added to the blaze of light which is Technion, creating an institute of technology that in the 3rd millennium is truly a light to the nations.

Keep it PURE – Nano filters for cleantech & desalination.

Handing you the Future ~
1912-2012: the Technion Centennial Stamp features
one application of the innovative nano fibers.
Featured on the Technion 2012 Cornerstone Centennial Stamp, the nanofibers behind the dynamic new start-up NanoSpun signify many of the secrets of Technion’s success in conceptualizing, shaping and nurturing Israel as the high-tech global success of the third millennium.

Why would Cornell University and New York City invite Technion to set up a new campus on Roosevelt Island, in order to boost economic growth through innovation and entrepreneurship? Throughout the world, news headlines have cited Technion’s unique ability to produce dynamic and profitable start ups using advanced technology and skills. In 2012, one company that exemplifies the secrets of this success is the prize-winning start up NanoSpun.
Cutting-edge innovation at the frontiers of multidisciplinary science, a streamlined, in-depth approach to technology transfer from the laboratory to the marketplace, and a powerful spirit of entrepreneurship that persists through the often turbulent process of making a raw innovation commercially viable: these are the known factors behind a universities ability to succeed on a national and international scale. And another factor, whispered in the halls of the successful: people – you need good people, that work together as a team.
“Success is all about people,” says Ohad Ben Dror, founder of NanoSpun, which after two years of intense groundwork was incorporated as a company in April of 2011. “You need a strong team that can work together well and drive the company to success.”
Versatile electrospun nanofibers –
taking global industry to a new dimension.
Backed by prominent investors, the versatile, hollow nanofiber innovation first emerged from the laboratory of Technion Prof. Eyal Zussman. The nanofibers first gained world attention with a prototype – an example of just one application – in the form of a nature-based tiny parachute that can be released in the sky and can sense and transmit the presence of biological pathogens or pollutants in the air. Unique and cost-effective in their fabrication, the fibers can also be tailored for applications in cleantech, medical devices, solar energy, textiles and packaging.
At the forefront of the young company’s present agenda is to apply the nanofibers in the world of cleantech – where there is a global demand for advanced and efficient systems for water and wastewater filtration and purification.
Based in the Gutwirth Science Park in Technion City, NanoSpun has already won world acclaim. In 2011, in Padua, Italy, the race was on at the Nano/Polymer Challenge as Nano entrepreneurs from across the world presented their innovative nanotechnologies, business plans, and long term vision to an international panel of judges. NanoSpun from the Technion’s Gutwirth Science Park, won the day, with first place in the Polymer category and a prize of 300,000 euros.
2011: Ohad Ben Dror of NanoSpun collects first prize among global start ups
in the field of nanotechnology at the Nano/Polymer Challenge in Italy.
Ohad Ben Dror was enticed into the exciting venture – which is now entering its second round of funding – through the Technion’s Entrepreneur in Residence Program (EIR). “T3 understands well the challenges of the entrepreneur…” says Ben Dror, “They know how to balance the needs of the entrepreneur with the academic perception. Creating a new start-up is always challenging and T3 helped a lot in this process.”
Holding several patents, and with a dedicated team of scientists, NanoSpun offers unique electrospun hollow nanofibers that – as world industries awaken to the competitive advantage of  the nano dimension – offer a revolutionary opportunity.For more information, contact NanoSpun. 

NanoSpun

CAMILA – Rocket Engine Ingenuity

Across the Universe – Rocket Engine Innovation

It takes energy to keep a satellite positioned in space, or to move a spacecraft to it’s destination. It also takes ASRI brainpower from Technion – Israel Institute of Technology.

Testing the Camila at ASRI’s Rocket Propulsion Lab.

When the iron curtain came down, a scientific opportunity emerged. World-class scientists were among the millions of Russians that were free to find America. Empowered by cultural diversity and open to newcomers, Technion’s Asher Space Research Institute (ASRI) seized the moment and recruited Prof. Alexander Kapulkin. Today, he is the mastermind of the world’s most efficient, fast and effective rocket engine, the CAMILA.

Downstairs at ASRI, the future of earth and space science is being born. In the new Rocket Propulsion Lab, suspended within a huge stainless steel vacuum cylinder, the hand-sized electric-propulsion hall thruster CAMILLA is undergoing tests. The lab took form through the combined skills of three immigrants from the former USSR. Kapulkin, his student from the University of Dnipropetrovsk in Ukraine Maxim Rubinovitch, and mechanical designer Dr. Vladimir Balabanov, who came to Israel 20 years ago from Omsk.CAMILA includes a revolutionary fuel-delivery design and an innovative magnetic field configuration that propels the engine faster. This innovation consumes less fuel, thus increasing engine efficiency. The impact will be less size, weight, and cost of small satellites. The new lab is set to be the only plasma process monitoring facility in Israel. CAMILA? The three scientists hope to experience her Sputnik moment within the next two years, when she will take her maiden voyage to propel her first microsatellite through space.

 

Patent Details: patents@tx.technion.ac.il

Highly efficient spacecraft thruster – CAMILA
Ref. MAE-0877
Background:
Hall Thrusters (HTs) are used in spacecraft to generate thrust by emitting particles at high velocities. Their low propellant consumption per unit of force allows them to be used for much longer times than rocket thrusters, which are short-lived. HTs work by ionizing gas particles in an anode cavity. The newly created ions exit the cavity and are drawn towards the opposite end of an acceleration channel by a strong electric field. When particles exit the channel at high speed into space, net thrust is induced on the channel. But, HTs suffer from relatively high power requirements. This is mainly due to the fact that some ‘slow’ ions collide with the anode walls, and do not exit the anode cavity into the acceleration channel.
Method:
Our technology increases Hall Thruster efficiency by significantly reducing the number of ‘slow ions’. Two major modifications contribute to the effect – unique geometry and an additional magnetic field. The acceleration channel is shaped like a cylinder, which has a low surface-to-volume ratio. This way, ions have higher chances of escaping the channel without colliding with the anode surface. The second modification is the addition of a longitudinal magnetic field inside the anode. This field lowers the electrical potential on the central cylindrical surface in respect to that of the anode, practically drawing ions away from the anode. As a result, the phenomenon of ‘slow ion waste’ is nearly eliminated. The added magnetic field can be generated by permanent magnets, which do not require additional power to operate.
Advantages:
• More than 100% increase in thrust without increase in propellant consumption
• Minute design and manufacturing modifications required 
• No additional power requirements in permanent magnet implementation
Applications:
Satellite and other spacecraft propulsion
Technological Keywords: Plasma, ion, thruster, hall, effect, electrons, electric, magnetic, field, xenon, gas, anode, cathode, accelerator, coil, pole, impulse
Market Keywords: space, satellite, rocket


Who’s Who at Technion: Prof. Daoud Bshouty

Mathematician Prof. Daoud Bshouty has pioneered geometric function theory of one complex variable, mathematical statistics and analytic probability theory. He has also innovated a Technion vision of multicultural harmony and continuously strives to improve life at Technion City on all levels. Meet Technion’s new Dean of Undergraduate Studies.

Technion’s new Dean of Undergraduate Studies: Prof. Daoud Bshouty.

Q: As Dean of Undergraduate Studies, what is your vision for the evolution of the
Technion student body over the next 10 years?

A: The centennial of the cornerstone of the Technion; The Nobel Prize in Chemistry for research professor Dan Shechtman; and the research center with Cornell in New York City; all mark a new era in Technion history, an international recognition of Technion researchers, teachers and students. Our excellent students represent the pioneers in in human knowledge in sciences and Technology and we look forward for more. In ten years from today I expect to see our campus in Haifa serving local and international students alike, and our graduates as embassadors of the technion worldwide.

Q: How would you describe morale among Technion students in 2012?

A: The year just started and our aim is to increase students morale throughout this year.  The Technion is known to impose on its students high load of study which affects students ‘ morale. We aim at making the studies a joyful experience without compromising the standarts of studies, this by rebuilding our curricula  to be less stressful, making the Technion  a village of students, faculty and administration a harmonious environment in which each group support the other.

Q: Can you give some keywords that distinguish Technion students from other students around the globe?

A: Hard workers, ambitious in a stubborn way, always unsatisfied from their lecturers yet they wouldn’t choose another place.

Q: Could you talk a little about Technion as a multicultural and increasingly international place to study?

A: In ten years from now i wont need to talk about that, the world will. But for now, since the 1990’s our society has become more and more  multicultural, yet  we still have a long way to accept it. Haifa itself is different in that respect and so is the Technion as part of the city. The technion also hosts many international students and researchers for long periods and  that is an extra experience that we add to the experience of our students.

Q: Why is recognition of difference an important part of a successful learning environment?

A: Learning is the experience of transferring knowledge and most productive in group discussions. Recognizing the different is simply to benefit from the experiences of other traditions and cultures.

Technion Trinity in Space

Formation flying mini satellites under development at the Asher Space Research Institute.

Technion researchers are planning to launch three nano-satellites of up to 6kg each into
space. The project was unveiled to global space agency representatives and space
researchers on January 30, 2012 at the Ilan Ramon International Space Conference of the
Israel Ministry of Science and Technology and the Fisher Institute.

“For the first time ever, an attempt will be made to launch three satellites that will fly
together in a controlled formation. To date, such a launch was not possible due to the size
and weight of the satellites, and because of the problems associated with the launch of
satellites in a uniform formation and their prolonged stay in space”, says Prof. Pini Gurfil of
the Faculty of Aerospace Engineering and the Asher Space Research Institute.

The Technion researchers aim the launch the experimental trio in 2015. The satellites will
attempt to receive signals from Earth at given frequencies, and to calculate the location of
the transmission’s origin. The receiving of signals transmitted from Earth to space using
several nano-satellites flying in formation is an experiment that no man has ventured before.
If it succeeds, formation flying nano satellites can be developed further for applications such
as locating survivors in disaster zones.

Another aim of the experiment is to prove that a uniform, controlled formation of satellites
can be held for one year in a 600 km orbit above Earth. For this purpose, researchers are
planning to install on each of the satellites a propulsion system that will assist in maintaining
the formation in space longer.

The satellites are planned to be built based on a CubeSat standard structure, whose parts will
be assembled by the researchers with the assistance of students. The satellite formation
comprises of six cubes, each 10x10x10 cm, such that each satellite will have a 10x20x30 cm
box. These boxes will carry measuring instruments, antennae, computer systems, control
systems, and navigation instruments. The software and the algorithms that will manage the
flight are developed in the Distributed Space Systems Laboratory at the Technion’s Asher
Space Research Institute and the UAV cluster of the Autonomous Systems Program at the
Technion. The nano-satellite formation will be launched as a supplementary payload on an
existing launch, through Europe, Russia or India.

The ambitious project is based on a prototype that was designed by Prof. Gurfil thanks to a
1.5 million euro grant he received from the European Union. The Technion hopes to get
additional support that will enable the actual development of the micro-satellites and their
launch.

“If we manage to prove in the experiment that the formation flight is possible, this will
provide a momentum to the development of small satellites and technologies related to the
miniaturization of electronic components, to efficient processing in space and to space
propulsion systems. These technologies could contribute to a variety of civil applications and
to the advancement of the Israeli space industry”, says Prof. Gurfil and adds: “another goal
of the project is to contribute to the practical training of space engineers, which is why
undergraduate and graduate students will fill practical roles in the examination of various
aspects related to the mission and in the development of the system. The designated training
and practical experience of space engineers are essential to Israel’s future in this field”.

In July 1998, researchers and students of the Faculty of Aerospace Engineering at the
Technion launched the satellite Gurwin TechSAT 2. The satellite, one of the smallest satellites
of its kind in the world, succeeded in remaining in space and completing all its tasks for
about 12 years.


————————.

Ready for Day Zero – Pioneering Cyber Security

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December 20th, 2030. The world has made headway into healing some of its oldest diseases
– cancer, Alzheimer’s, MS. Driven by global communication through social media, the majority
of nations are at peace, as the problem of oil dependency was alleviated by energy pioneers
that created unlimited fuel from an infinite resource the sun.


But on that morning of hope and global stability, it all went wrong. A disparate doomsday
group from a remote rogue nation, managed to hack into the central control system of the US
nuclear missiles program. Nuclear warheads filled the skies like a plague of hornets, without
method in the madness – without a visible enemy to deter – without a whisper of hope for the
survival of the human race.


An extreme and unrealistic scenario, yet with the advancement and popularity of IT, the
recent cyber squabble – apparently between teenage hackers from Saudi Arabia and Israel in
a battle to affirm who could dash the death-blow in a cyber confrontation – brought the issue
of cyber security again to the foreground of the international security agenda.


“This is not serious stuff,” said Prof. Erez Petrank, a Technion encryption expert interviewed
on the recent cyber punch-out by the National Cyber Security website in the US.


“These hackers are being presented as geniuses. Most of them are simply very patient. They
download a number of tools which they don’t even build themselves, and attack and attack
sites until they find one that isn’t secure.”

“Israel is exposed to cyber-attacks which can paralyze entire life systems on which the country runs.”

PM Netanyahu.



In Israel, it turns out, great minds are contemplating possible Day Zero possibilities. Not
the teenage Saudi ‘nightmare’ – as the ambitious hacker called himself – but the real
NIGHTMARE. And at Technion’s world-leading computer science faculty, plans are underway
to bring expert researchers from across the field into one Cyber Security Research and
Teaching Program at the Faculty of Computer Science.


For experts like Petrank, the kind of “Day Zero” scenario such as sabotage of power plants,
flight control systems, or army control networks are far more disturbing. “Al Qaeda are looking
for more spectacular ways to wage war. They are looking for something more dramatic than
9/11, and that can either be the acquisition of weapons of mass destruction or cyber terrorism
— real cyber terror,” an Israel cyber terror expert told reporters. “Events like these of the past
few weeks can pique their interest in true cyber warfare.”


Real cyber terror involves hitting control systems of airports or other infrastructure, power
plants, transportation systems, hospitals, everything that is controlled by computers. The
damage could be catastrophic – far more than a conventional war. “This could involve the
killing of thousands of people. Imagine someone breaking into Logan airport’s systems, and
instead of hijacking planes, now they are programmed to collide into one another or crash.”


Israel’s enemies are probing the vulnerability of these sophisticated systems. Israeli PM
Benjamin Netanyahu recently warned that “Israel is exposed to cyber-attacks which can


paralyze entire life systems on which the country runs.” To face the constant threat of attacks
by terrorists and hostile countries, it is absolutely vital to Israel’s security and economic well-
being to develop the best, most robust systems and take all measures possible to protect
them. Therefore, Prime Minister Netanyahu has recently announced “the establishment of a
national cybernetic initiative to encourage and develop the field of cybernetics and turn the
State of Israel into a global center of [cybernetics] knowledge, in cooperation with academia,
industry, the security establishment and other public bodies.”


Technion is well known for various contributions in computer security and cryptography, such
as assessing the security of cellular phone networks and exposing their vulnerabilities and
weaknesses.


For example, a Technion team studied the protocols of the ubiquitous GSM phone system
and identified several weaknesses that allowed for eavesdropping on a conversation, taking
over a call, and even impersonating a different phone owner. The researchers also examined
the security of other kinds of applications such as car remote controls, analysis of the strength
of cryptographic standards, and the design of new cryptographic systems.


In addition, Technion researchers working in other areas of computing constantly address
security issues such as cloud computing, where security is a critical enabling technology
without which the entire concept is rendered unusable.


Researchers in a variety of Technion faculties study security issues related to operating
systems (OS), the methodologies by which they defend underlying applications, and
requirements from supporting hardware and programming languages.


Technion graduates have become key players in Israel’s thriving computer security industry.
A good example is the startup, Imperva , which recently went public and works in the area
of data protection. One of its founders was also a founder of Checkpoint, a leading Israeli
company that revolutionized computer security in the early 1990s, making it possible for
enterprises to defend entire networks. Its magnitude of success has paved the way and
inspired many other Israeli companies and Technion graduates. In today’s Israeli high-tech
arena, an entire ecosystem of companies exists to seek out solutions for the next possible
cyber flaw. One would be hard-pressed to find such a company without a dominant presence
of Technion graduates.


File:Computer hacking.jpg
When a hacker becomes a WMD terrorist –
Technion Research blocks the way.

Atidim – Empowering Our Future.

“Someone is investing in me, and I will try my hardest to succeed.


Photo: Atidim.
Growing up in a family with four siblings in Beit Shean, a periphery town on Israel’s northeastern border  with  Jordan, Shir Paska could not take a place in Israel’s top university for granted. She knew she wanted to do something in engineering or 
computers. 
Shir was ecstatic when she was accepted. “There are only 41 people chosen for this program and I  so  much  wanted  to  be  one  of  them. Someone is investing so much in me, and I will try my hardest to do the maximum and succeed.”
This year, Shir becomes a freshman in mechanical engineering at the Technion. She will receive a scholarship, laptop computer and living expenses through Rosman Atidim’s Industry program, and intern in her field at a leading company. 
“I want to get my degree and live and work in the North,” says Shir. “The Galilee has too much wasted potential, and I want to change that. Rosman Atidim is giving me the chance.”
Founded with the support of Dr. Martin and Grace Rosman of Sarasota Florida and Edgewater Maryland, the Rosman Atidim program supports Atidim’s PreAcademic Preparatory and Industry program at the Technion – Israel Institute of Techology. It provides the means to excel to talented young people from Israel’s less privileged neighborhoods. Students from the program often have a stated agenda to take their new skills back home – to advance their native area and inspire others to do the same.

Rosmans with Apeloig
Marty and Grace Rosman with Distinguished Prof. Yitzhak Apeloig.

The Rosman’s have been supporting Atidim students at the Technion for the past four years. All of the 20 students from the first graduating class are working in their respective professions in industry. In 2011/12, the Rosman Atidim Industry program is supporting 53 freshman students, of which 28 are graduates of the Pre-Academic Preparatory Program, and 47 sophomores. An additional 40 students will begin the Pre-Academic Preparatory program in January 2012.  

Atidim students receive assistance in every aspect of university life. From financial scholarships to academic tutoring, personal coaching to integration into the work force and even a laptop computer, these students know that someone believes in them and is willing to invest in their success. 

NANO Nutraceuticals – pioneering health.

Nanocapsules developed by Technion researchers from natural materials can also be used by the pharmaceutical industry – in the protection of medicines in the stomach and their release in the intestine, as well as for targeting cancerous tumors

Image Detail
Technion researchers have created nanocapsules that are based on natural food components, and trapped in them vitamins and nutraceuticals (health-enhancing micronutrients) that do not dissolve well in water. The nanocapsules can be added to clear beverages, thus increasing their health benefits without clouding them.
Dr. Yoav Livney and his team in the Faculty of Biotechnology and Food Engineering used the Maillard reaction to create nanocapsules based on the protein–polysaccharide conjugates. This natural reaction, which is the cause of the browning of food during baking and cooking, was used in the past in the creation of emulsions and microcapsules for nutrients that do not dissolve in water, but the problem with the existing methods is that the capsules obtained were large, so that they clouded the liquid they were added to.
To overcome this problem, Dr. Livney and his team conjugated maltodextrin, a product of the breakdown of starch into Casein, milk protein, in a controlled process. The conjugated molecules (conjugates) underwent spontaneous self-assembly into capsules of nanometric dimensions. These nanocapsules are so small, that the beverages they were added to remained clear.
In the next stage, the researchers trapped in the nanocapsules vitamin D (large parts of the population suffer from vitamin D deficiency, which could cause rickets in children and many other health disorders in adults). The research team found that the nanocapsules protect the vitamins “packed” in them. “They protected the vitamin D from degrading in an acidic environment, and during its refrigerated shelf-life”, says Dr. Livney.
Another important material called EGCG (epigallocatechin gallate), that is found in green tea and that is considered to inhibit many diseases, among them are neurodegenerative diseases, cardiovascular diseases and cancer, was also significantly protected by the conjugates throughout its shelf-life.
The researchers also followed the release of the nutrients from the nanocapsules under simulated digestion conditions. They discovered that the nanocapsules succeeded in keeping the nutrients trapped in them, and in protecting them under stomach conditions. Livney believes that the enzymes in the small intestine will break the polysaccharide-protein envelope down easily, allowing the absorption of the nutritional nano-cargo at the desired location, in the small intestine.

In the future, Dr. Livney plans to “research the overall release profile of nutraceuticals through simulated digestion, and later to examine their bioavailability in vivo in clinical trials”. He adds that “we also intend to investigate the encapsulation by this method of other bio-active components, such as anti-cancer medicines.
Another team headed by Dr. Livney is currently developing the next generation of polysaccharide-protein conjugate-based nanocapsules, which are aimed at target-oriented delivery of medicines in the body, marking the location of cancerous tumors and destroying them.

Prior to becoming a faculty member in the Technion’s Faculty of Biotechnology and Food Engineering, Yoav Livney was involved in the development of “Gamadim”, “Ski” and “Symphony”, as part of his work as the product development manager of the cheese business unit at “Strauss”.

Nobel Prize Winning Ubiquitin in Action

Proteologics’ pioneers targeted drug development CEO Joshua Levin discusses the molecules being developed with Teva and GlaxoSmithKline.[Extracted from Globes, Israel]

The award of the 2011 Nobel Prize in Chemistry to Prof. Dan Schechtman, following the 2009 win by Prof. Ada Yonath, put the world of chemistry and Israel’s contributions to science that laypeople can barely understand in the limelight. Schechtman and Yonath have not yet turned their discoveries, of quasi-crystals and the mechanism of the ribosome, respectively, into commercial products, but their two Israeli predecessors, Prof. Aaron Ciechanover and Prof. Avram Hershko, the 2004 Nobel Laureates in Chemistry, have succeeded in doing so (or at least trying). They contributed their know-how and reputations to Proteologics Ltd. (TASE: PRTL).

Ubiquitin – the new buzzword

To understand what Proteologics is doing, it is necessary to go back to high school chemistry and the stubborn teacher who tried to explain what a protein is. The company is developing targeted therapeutics for the ubiquitin system, which regulates almost all aspects of eukaryotic cellular function, including cell cycle regulation, DNA repair, signal transduction, immune response, protein quality control and metabolism. The system comprises about 1,000 protiens.
Hershko and Ciechanover discovered the ubiquitin system in 1978, and jointly won the Nobel Prize in Chemistry in 2004 for the discovery. They are both members of Proteologics’ science advisory board.
Targeted medications are not regular drugs; as their name implies, they have just one specific target, and are consequently more effective, (improving a patient’s quality of life by reducing the side effects of treatment) and are more efficient for health funds by cutting costs. These drugs discover the proteins that play an important role in a disease, neutralizing which leads to improvement, even a cure, for the disease in question.
A ubiquitin is a small regulatory protein that can be attached to proteins and label them for destruction for the proper function of the cell. Ubiquitin tags can also direct proteins to other locations in the cell, where they control other protein and cell mechanisms. Disruption of the ubiquitin system is therefore liable to cause a wide range of diseases, including cancers, diseases of the nervous system such as Alzheimer’s or Parkinson’s, muscular dystrophy, and viral diseases.
Drug development is complicated, and the difficulties are compounded in the case of the ubiquitin system. It is a hierarchal cascade system with three levels: The E1 enzyme is a single protein, which can bind with the subordinate level, E2 enzymes (of which there are about 40), which in turn influence the more than 600 E3 enzymes.
This hierarchal cascade and the multiple E2-E3 connections complicates the drug development task. E3 enzymes directly transfer the signal to the protein, and this is where Proteologics finds the proteins that are the basis for its therapeutics. Any intervention higher up in the hierarchy is liable to cause harm rather than help.
Business model: spread the risk
Proteologics’ business model may prove in future to be much more effective than the models of other R&D companies. The drug development and approval process has three main stages. First is identification of the target and development of a suitable molecule, which is followed by preclinical and human clinical trials.
Proteologics only operates at the first and second stages, while the final stage, which requires more time and financial investment, is handled by the company’s big pharma partners – Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA; TASE: TEVA) and GlaxoSmithKline plc (NYSE; LSE: GSK).
In this way, Proteologics reduces its financial risk, as the clinical trial and most expensive stage is carried out by big pharma companies which bear the financial risk. Proteologics even receives advances for R&D costs, which are partly covered by its partners. The company also has an option for receiving milestone payments, and will receive generous royalties from sales, assuming that the drug is approved for marketing.
Until that day comes, if it ever does, Proteologics can use the milestone payments to pursue additional projects on the basis of the platform it developed for working with E3 enzymes with different tags. This enables the company to survive, in theory, for a long time as it expands its knowledge and its platform to create a large enough product base that will increase its chances of turning at least one of its drug candidates into a commercial product.
Proteologics CEO Joshua Levin says that it has been able to lower its risk profile by choosing two partners that complements each other, in both character and terms of the agreements signed with them. GlaxoSmithKline, a UK giant with a market cap of $117 billion, is developing with Proteologics six programs for the treatment of various cancers (each program is based on a different E3 enzyme). Teva is jointly developing three programs. Proteologics is also developing two programs independently, and will either continue to do so or find a partner.
“GlaxoSmithKline and Teva complement each other,” says Levin. “Teva is not an innovative company, which is why it chose to invest a little in us now, and give us a larger share of revenue from drug sales. GlaxoSmithKline, in contrast, chose to invest much more in us at the first and second stages, and took a greater share for itself when the drug reaches market.”
In the case of GlaxoSmithKline, which is the more important partner for Levin, each program could generate up to $176 million in royalties, or up to $1 billion altogether, but Levin is realistic about these numbers. “This isn’t a real number. There’s no chance that all six drugs will be commercialized,” he says.

2012 is the critical year

Under Proteologics’ timetable, 2012 will be a critical year. Teva, which has undergone quite a few changes, mainly as a result of its acquisition of Cephalon, is scheduled to receive its first molecule from Proteologics within months, and will have to decide whether it wants to pursue development. If it chooses not to do so, Proteologics can continue development (a Phase I clinical trial) independently, or find another partner, without the need to start the development process from scratch.
Levin is not worried that either Teva or GlaxoSmithKline will return molecules to the company, but he is nonetheless doing everything to make sure that does not happen. In the case of GlaxoSmithKline, each program has a three-year timeframe, which means that in early 2013, Proteologics will have to hand over the first molecule to it and wait for a response.
Read full article at Globes

Israel: Land of the Little Apple




High-tech Giant Apple to set up Israel development center

With Technion graduates heading R&D centers for Microsoft, Yahoo, Google and Intel to name a view, Apple has until now been noticeable by it absence. Now, news is surfacing that Technion graduate (first and second degrees) Aharon Aharon will head Apple’s first ever development center outside of its California headquarters.
Apple Inc. has decided to open a development center in Israel focusing on semiconductors, the first R&D venture for the company outside the United States, the Israeli Business news service Globes Wednesday. The decision was apparently made even before the company entered into talks to acquire Herzliya-based flash storage solutions provider Anobit Ltd.

Apple has hired Aharon Aharon, Technion graduate and a veteran player in Israel’s high tech industry, to lead the new development center. The planned Israel center will be the company’s first such center outside of its California headquarters.

Aharon Aharon comes to Apple with a rich background. His most high-tech venture was Camero Tech Ltd., which develops Radio Frequency (RF) based imaging systems, and which he founded in 2004 with Amir Beeri. Before that, he was chairman of embedded security solutions developer Discretix Inc. and managed their Israel development center. He was also VP operations at Zoran Corp.(Nasdaq: ZRAN), having begun his career at IBM’s Haifa development center where he reached the post of deputy director.

Apple is cultivating it;s new orchard for future growth fast. Aharon will be spending some months at Apple HQ in Cupertino before launching the Israel enterprise and harvesting the local skills and ingenuity. It is one ground breaking decision that is sure to support Apple in maintaining its competitive edge in the next, even smarter generation.

The Birth of Super Resolution – Technion Startup in HD!

A clear-cut example of the dynamic process of technology transfer at the Technion – the startup BETTERview is slated to revolutionize the quality of HD imaging – by taking and applying new research from the Technion department of electrical engineering all the way to your the screen of your TV, PC or smart phone. Have something old and cloudy? BETTERvIew also offers a conversion service to produce images as crisp as if they were filmed with the cutting-edge cameras of tomorrow.


BETTERView offers SD to true HD (High Definition) conversion and video enrichment. Check the following video to see the quality advantage.




The patented breakthrough in the super resolution promises to breaks the “glass ceiling” of existing technology, says the company, whose team includes world-experts from Technion’s Faculty of Computer Science, which is ranked #15 in the world. While conventional methods use conversion techniques to “blow up” or stretch the SD video onto an HD display, BetterVirw increases optical resolution of a video stream, generating an HD stream that looks as authentic as it gets.


BETTERview technology is based on a novel family of SR algorithms, proposed by a world-leader in this field, Prof. Michael Elad (Technion – Israel Institute of Technology). Elad and his collaborator, Dr. Matan Protter devised the first method that overcomes the requirement for very accurate and explicit motion estimation in previous SR technologies. The new family of SR techniques avoids the exact motion estimation and replaces it by a probabilistic estimate. This enables handling successfully general content scenes containing extremely complex motion patterns. 


The results are impressive, with no visual artifacts, and the process is completely robust. Based on this core technology, BETTERview developed the first cutting-edge industrial-grade robust system that perform SD to True HD resolution conversion. Its solution strengthens the above-mentioned core technology by handling various video artifacts, interlaced content, synchronization issues and run-time efficiency.


The innovative research of Prof. Michael Elad was listed in 2010 by Thomson Reuters Science Watch. You can read their interview with him here.



It has been known for the past 20 years that, in principle, one could take several low-quality images and fuse them into a single, higher-resolution outcome. This has been demonstrated by scientists, adopting various techniques and algorithms. The process is known as Super-Resolution (SR), which  became a hot field in image processing, with thousands of academic papers published during the past two decades on the problem and ways to handle it. The classical approach to fuse the low-quality images requires finding an exact correspondence between their pixels, a process known as “motion estimation”. Several years ago this field experienced a revolution, due to a breakthrough in the way to handle (or better yet, bypass altogether) the motion estimation.